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NLRP3-IN-71

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Catalog No. T204007Cas No. 3026419-44-0

NLRP3-IN-71 (Compound 19) is an orally active and selective NLRP3 inhibitor that can cross the blood-brain barrier and inhibit IL-1 β secretion. Can be used for research on neurodegenerative diseases.

NLRP3-IN-71

NLRP3-IN-71

😃Good
Catalog No. T204007Cas No. 3026419-44-0
NLRP3-IN-71 (Compound 19) is an orally active and selective NLRP3 inhibitor that can cross the blood-brain barrier and inhibit IL-1 β secretion. Can be used for research on neurodegenerative diseases.
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10 mgInquiry7-10 days
50 mgInquiry7-10 days
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Product Introduction

Bioactivity
Description
NLRP3-IN-71 (Compound 19) is an orally active and selective NLRP3 inhibitor that can cross the blood-brain barrier and inhibit IL-1 β secretion. Can be used for research on neurodegenerative diseases.
Chemical Properties
Molecular Weight392.38
FormulaC18H19F3N6O
Cas No.3026419-44-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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