Shopping Cart
- Remove All
Your shopping cart is currently empty
ODN MT01
Catalog No. T87059Cas No. 1817821-77-4
ODN MT01, designed based on human mitochondrial DNA sequences, is an inhibitory ODN that promotes osteocyte differentiation. It enhances osteoblast maturation and activation in rats, reduces alveolar bone absorption due to periodontitis, and regulates the expression levels of osteogenesis-related factors.
ODN MT01
ODN MT01
Catalog No. T87059Cas No. 1817821-77-4
ODN MT01, designed based on human mitochondrial DNA sequences, is an inhibitory ODN that promotes osteocyte differentiation. It enhances osteoblast maturation and activation in rats, reduces alveolar bone absorption due to periodontitis, and regulates the expression levels of osteogenesis-related factors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | ODN MT01, designed based on human mitochondrial DNA sequences, is an inhibitory ODN that promotes osteocyte differentiation. It enhances osteoblast maturation and activation in rats, reduces alveolar bone absorption due to periodontitis, and regulates the expression levels of osteogenesis-related factors. |
| In vitro | ODN MT01 enhances the proliferation and differentiation of BMSCs into osteoblasts, while also promoting the mRNA expression of Runx2, Osterix, OPG, RANKL, and collagen I. [2]. Additionally, ODN MT01 affects the cell cycle of MG63 cells, facilitating their proliferation. [3]. |
| In vivo | ODN MT01 inhibits alveolar bone loss in rats with periodontitis and induces the production of OPG and Osterix proteins in bone tissue [2]. |
| Cas No. | 1817821-77-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy ODN MT01 | purchase ODN MT01 | ODN MT01 cost | order ODN MT01 | ODN MT01 in vivo | ODN MT01 in vitro
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.