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P-selectin antagonist 1

Catalog No. T88079Cas No. 2099111-75-6

Compound 11b, known as P-selectin antagonist 1, serves as an antagonist for both pan-selectin, with an IC50 of 82 μM, and E-selectin, with a KD of 0.91 μM.

P-selectin antagonist 1

P-selectin antagonist 1

Catalog No. T88079Cas No. 2099111-75-6
Compound 11b, known as P-selectin antagonist 1, serves as an antagonist for both pan-selectin, with an IC50 of 82 μM, and E-selectin, with a KD of 0.91 μM.
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Product Introduction

Bioactivity
Description
Compound 11b, known as P-selectin antagonist 1, serves as an antagonist for both pan-selectin, with an IC50 of 82 μM, and E-selectin, with a KD of 0.91 μM.
Chemical Properties
Molecular Weight1402.34
FormulaC56H71N5Na4O25S3
Cas No.2099111-75-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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