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PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. It is less potent than PAF C-16 and PAF C-18 in the induction of neutrophil chemotaxis, but is equipotent to PAF C-16 and PAF C-18 in promoting eosinophil migration. PAF C-18:1 activates the PAF receptor and has been used in antibody binding experiments to determine the importance of an acyl linkage at the sn-2 position for recognition at this receptor.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $198 | 35 days | |
10 mg | $365 | 35 days | |
25 mg | $865 | 35 days |
Description | PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. It is less potent than PAF C-16 and PAF C-18 in the induction of neutrophil chemotaxis, but is equipotent to PAF C-16 and PAF C-18 in promoting eosinophil migration. PAF C-18:1 activates the PAF receptor and has been used in antibody binding experiments to determine the importance of an acyl linkage at the sn-2 position for recognition at this receptor. |
Molecular Weight | 549.73 |
Formula | C28H56NO7P |
Cas No. | 85966-90-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O: 20 mg/mL DMF: 10 mg/mL DMSO: 10 mg/mL PBS (pH 7.2): 20 mg/mL Ethanol: 10 mg/mL |
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