Patuletin

Patuletin, a flavonol isolated from the flowers of Tagetes patula, exhibits anti-proliferative activity against cancer cells, induces significant nuclear fragmentation, and has a high capacity to activate caspase-3 [1] [2].

Catalog No. TN7756Cas No. 519-96-0

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Patuletin

Catalog No. TN7756Cas No. 519-96-0

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Product Introduction

Bioactivity

Description	Patuletin, a flavonol isolated from the flowers of Tagetes patula, exhibits anti-proliferative activity against cancer cells, induces significant nuclear fragmentation, and has a high capacity to activate caspase-3 [1] [2].
In vitro	Patuletin (0-100 μg/mL, 24 h) demonstrated anticancer activities by inhibiting cell proliferation and inducing apoptosis in CaSki, MDA-MB-231, and SK-Lu-1 cell lines [2]. The compound exhibited a dose-dependent inhibition of cell proliferation in these cell lines, with IC50 values of 37, 86, and 18 μg/mL for CaSki, MDA-MB-231, and SK-Lu-1 cells, respectively.

Chemical Properties

Molecular Weight	332.26
Formula	C₁₆H₁₂O₈
Cas No.	519-96-0

Storage & Solubility Information

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Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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