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PC-PEG11-Azide is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | PC-PEG11-Azide is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together, with one binding to an E3 ubiquitin ligase and the other to the target protein, thereby utilizing the ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 455.468 |
Formula | C19H29N5O8 |
Cas No. | 2353409-89-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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