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PD-1-IN-25 (compound 43) serves as a powerful inhibitor of the PD-1/PD-L1 interaction, boasting an impressive IC50 of 10.2 nM, as measured in the HTRF assay. By impeding PD-1/PD-L1 cellular signaling, PD-1-IN-25 facilitates the activation of CD8+ T cells. Furthermore, it has been shown to delay tumor growth [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | PD-1-IN-25 (compound 43) serves as a powerful inhibitor of the PD-1/PD-L1 interaction, boasting an impressive IC50 of 10.2 nM, as measured in the HTRF assay. By impeding PD-1/PD-L1 cellular signaling, PD-1-IN-25 facilitates the activation of CD8+ T cells. Furthermore, it has been shown to delay tumor growth [1]. |
Molecular Weight | 725.13 |
Formula | C37H35ClF2N2O9 |
Cas No. | 2413100-40-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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