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PD-1/PD-L1-IN-47

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Catalog No. T89171Cas No. 1137341-95-7

PD-1/PD-L1-IN-47 (MolPort-001-742-690) is a pH-selective inhibitor of the PD-1/PD-L1 signaling pathway, demonstrating significant affinity for PD-L1 under acidic conditions and lower toxicity. It is utilized in the study of tumors.

PD-1/PD-L1-IN-47

PD-1/PD-L1-IN-47

😃Good
Catalog No. T89171Cas No. 1137341-95-7
PD-1/PD-L1-IN-47 (MolPort-001-742-690) is a pH-selective inhibitor of the PD-1/PD-L1 signaling pathway, demonstrating significant affinity for PD-L1 under acidic conditions and lower toxicity. It is utilized in the study of tumors.
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
PD-1/PD-L1-IN-47 (MolPort-001-742-690) is a pH-selective inhibitor of the PD-1/PD-L1 signaling pathway, demonstrating significant affinity for PD-L1 under acidic conditions and lower toxicity. It is utilized in the study of tumors.
Chemical Properties
Molecular Weight484.45
FormulaC22H28O12
Cas No.1137341-95-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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