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PDE4-IN-5

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Catalog No. T61295

PDE4-IN-5 (compound 33a) is a highly potent and selective PDE4 inhibitor with an IC50 value of 3.1 nM, exhibiting excellent skin permeability and a well-characterized binding mechanism. It also shows a notable anti-psoriasis effect [1].

PDE4-IN-5

PDE4-IN-5

😃Good
Catalog No. T61295
PDE4-IN-5 (compound 33a) is a highly potent and selective PDE4 inhibitor with an IC50 value of 3.1 nM, exhibiting excellent skin permeability and a well-characterized binding mechanism. It also shows a notable anti-psoriasis effect [1].
Pack SizePriceAvailabilityQuantity
25 mg$1,52010-14 weeks
50 mg$1,98010-14 weeks
100 mg$2,50010-14 weeks
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Product Introduction

Bioactivity
Description
PDE4-IN-5 (compound 33a) is a highly potent and selective PDE4 inhibitor with an IC50 value of 3.1 nM, exhibiting excellent skin permeability and a well-characterized binding mechanism. It also shows a notable anti-psoriasis effect [1].
Chemical Properties
Molecular Weight356.46
FormulaC21H28N2O3
Storage & Solubility Information
StorageShipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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