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PF-06456384

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Catalog No. T28371Cas No. 1834610-73-9
Alias PF-6456384, PF6456384, PF06456384, PF 6456384, PF 06456384

PF-06456384 is a highly potent and selective NaV1.7 inhibitor with an IC50 value of 0.01 nM (nanomolar).

PF-06456384
Other Forms of PF-06456384:
PF-06456384 trihydrochlorideT738461834610-75-1
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PF-06456384

😃Good
Catalog No. T28371Alias PF-6456384, PF6456384, PF06456384, PF 6456384, PF 06456384Cas No. 1834610-73-9
PF-06456384 is a highly potent and selective NaV1.7 inhibitor with an IC50 value of 0.01 nM (nanomolar).
Pack SizePriceAvailabilityQuantity
25 mg$1,9708-10 weeks
50 mg$2,5808-10 weeks
100 mg$3,4008-10 weeks
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Product Introduction

Bioactivity
Description
PF-06456384 is a highly potent and selective NaV1.7 inhibitor with an IC50 value of 0.01 nM (nanomolar).
AliasPF-6456384, PF6456384, PF06456384, PF 6456384, PF 06456384
Chemical Properties
Molecular Weight719.8
FormulaC35H32F3N7O3S2
Cas No.1834610-73-9
Relative Density.1.46 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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PF-06456384
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