Shopping Cart
- Remove All
- Your shopping cart is currently empty
PF-06761281 (Compound 4a) is a potent, orally active, partial selective inhibitor of the sodium-coupled citrate transporter (NaCT or SLC13A5), with IC50 values of 0.51 μM for HEK NaCT, 13.2 μM for HEK NaDC1, and 14.1 μM for HEK NaDC3 [1].
Description | PF-06761281 (Compound 4a) is a potent, orally active, partial selective inhibitor of the sodium-coupled citrate transporter (NaCT or SLC13A5), with IC50 values of 0.51 μM for HEK NaCT, 13.2 μM for HEK NaDC1, and 14.1 μM for HEK NaDC3 [1]. |
In vitro | PF-06761281 (Compound 4a) effectively inhibits citrate uptake in rat, mouse, and human hepatocytes (Heps), demonstrating inhibition concentration 50 (IC50) values of 0.12, 0.21, and 0.74 μM, respectively [1]. |
Molecular Weight | 283.28 |
Formula | C13H17NO6 |
Cas No. | 1854061-19-0 |
Storage | Shipping with blue ice. |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.