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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $30 | Backorder |
Description | Propargyl-PEG6-NH2 is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras] that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together: one binding to an E3 ubiquitin ligase and the other to the target protein, thereby leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 319.39 |
Formula | C15H29NO6 |
Cas No. | 1198080-04-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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