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PROTAC BRD4 Degrader-17

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Catalog No. T74270Cas No. 2585561-49-3

PROTAC BRD4 Degrader-17 (compound 13i), a potent inhibitor, exhibits IC50 values of 29.54 nM (BRD4 (BD1)) and 3.82 nM (BRD4 (BD2)), effectively reducing Cyclin B1 expression linked with G2/M phase progression and significantly inducing apoptosis in MV-4-11 cells [1].

PROTAC BRD4 Degrader-17

PROTAC BRD4 Degrader-17

😃Good
Catalog No. T74270Cas No. 2585561-49-3
PROTAC BRD4 Degrader-17 (compound 13i), a potent inhibitor, exhibits IC50 values of 29.54 nM (BRD4 (BD1)) and 3.82 nM (BRD4 (BD2)), effectively reducing Cyclin B1 expression linked with G2/M phase progression and significantly inducing apoptosis in MV-4-11 cells [1].
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Product Introduction

Bioactivity
Description
PROTAC BRD4 Degrader-17 (compound 13i), a potent inhibitor, exhibits IC50 values of 29.54 nM (BRD4 (BD1)) and 3.82 nM (BRD4 (BD2)), effectively reducing Cyclin B1 expression linked with G2/M phase progression and significantly inducing apoptosis in MV-4-11 cells [1].
Chemical Properties
Molecular Weight877.94
FormulaC49H47N7O9
Cas No.2585561-49-3
Storage & Solubility Information
StorageShipping with blue ice.

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