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PROTAC erf3a Degrader-2
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Catalog No. T89327Cas No. 3033871-15-4
PROTACerf3a Degrader-2 (Compound C59) is an orally active degrader of PROTACerf3a that suppresses the expression levels of SRD5A3 and GSPT1 (eRF3a). It inhibits the proliferation of cancer cells, such as in 22Rv1. PROTACerf3a Degrader-2 is utilized in research for various cancers including prostate, ovarian, liver, cervical, leukemia, and breast cancer.
PROTAC erf3a Degrader-2
😃Good
Catalog No. T89327Cas No. 3033871-15-4
PROTACerf3a Degrader-2 (Compound C59) is an orally active degrader of PROTACerf3a that suppresses the expression levels of SRD5A3 and GSPT1 (eRF3a). It inhibits the proliferation of cancer cells, such as in 22Rv1. PROTACerf3a Degrader-2 is utilized in research for various cancers including prostate, ovarian, liver, cervical, leukemia, and breast cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Chemical Properties
| Description | PROTACerf3a Degrader-2 (Compound C59) is an orally active degrader of PROTACerf3a that suppresses the expression levels of SRD5A3 and GSPT1 (eRF3a). It inhibits the proliferation of cancer cells, such as in 22Rv1. PROTACerf3a Degrader-2 is utilized in research for various cancers including prostate, ovarian, liver, cervical, leukemia, and breast cancer. |
| Molecular Weight | 760.92 |
| Formula | C44H52N6O6 |
| Cas No. | 3033871-15-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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