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Protoescigenin 21-tiglate

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Catalog No. TN8113Cas No. 7047-43-0
Alias (E)-21-Angeloyl-protoaescigenin

Protoescigenin 21-tiglate (compound 10), a type of Bayberry Triterpenoid Saponin (BAT), can be isolated from the acidic hydrolyzed products (AHP) of a crude extract derived from bayberry seeds. BATs are generally known for their robust anti-tumor, anti-inflammatory, and anti-Alzheimer’s activities. However, the anti-tumor activity of Protoescigenin 21-tiglate is relatively weak, with inhibitory concentrations (IC50) exceeding 80 μM for MCF-7 and at 80 μM for HeLa cells.

Protoescigenin 21-tiglate

Protoescigenin 21-tiglate

😃Good
Catalog No. TN8113Alias (E)-21-Angeloyl-protoaescigeninCas No. 7047-43-0
Protoescigenin 21-tiglate (compound 10), a type of Bayberry Triterpenoid Saponin (BAT), can be isolated from the acidic hydrolyzed products (AHP) of a crude extract derived from bayberry seeds. BATs are generally known for their robust anti-tumor, anti-inflammatory, and anti-Alzheimer’s activities. However, the anti-tumor activity of Protoescigenin 21-tiglate is relatively weak, with inhibitory concentrations (IC50) exceeding 80 μM for MCF-7 and at 80 μM for HeLa cells.
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Product Introduction

Bioactivity
Description
Protoescigenin 21-tiglate (compound 10), a type of Bayberry Triterpenoid Saponin (BAT), can be isolated from the acidic hydrolyzed products (AHP) of a crude extract derived from bayberry seeds. BATs are generally known for their robust anti-tumor, anti-inflammatory, and anti-Alzheimer’s activities. However, the anti-tumor activity of Protoescigenin 21-tiglate is relatively weak, with inhibitory concentrations (IC50) exceeding 80 μM for MCF-7 and at 80 μM for HeLa cells.
Alias(E)-21-Angeloyl-protoaescigenin
Chemical Properties
Molecular Weight588.82
FormulaC35H56O7
Cas No.7047-43-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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