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RC-106
RC-106, a proteasome inhibitor (IC50: 35 μM) and Sigma receptor modulator, exhibits anticancer activity and antiproliferative effects against cancer cells, including glioblastoma (GB) and multiple myeloma (MM) [1].
Catalog No. T87296Cas No. 1346216-50-9
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RC-106
Catalog No. T87296Cas No. 1346216-50-9
RC-106, a proteasome inhibitor (IC50: 35 μM) and Sigma receptor modulator, exhibits anticancer activity and antiproliferative effects against cancer cells, including glioblastoma (GB) and multiple myeloma (MM) [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Bioactivity
Chemical Properties
| Description | RC-106, a proteasome inhibitor (IC50: 35 μM) and Sigma receptor modulator, exhibits anticancer activity and antiproliferative effects against cancer cells, including glioblastoma (GB) and multiple myeloma (MM) [1]. |
| In vitro | RC-106, when administered at a concentration of 60 μM for 24 hours, was found to inhibit the viability of cancer cells [1]. In a cell viability assay [1] using U87-MG cells, RC-106 demonstrated moderate activity. Specifically, at concentrations of 40 and 60 μM over an incubation period of 24 hours, it notably reduced cell viability to 34% at the higher concentration. |
| Molecular Weight | 355.52 |
| Formula | C26H29N |
| Cas No. | 1346216-50-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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