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Reltecimod TFA

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Catalog No. T78107
Alias AB-103 TFA

Reltecimod (AB-103) TFA is an antagonist of the T-cell-specific surface glycoprotein CD28 (TP44), demonstrating efficacy against various bacterial infections, including exotoxins, endotoxins, and ionizing radiation. By modulating the inflammatory response through attenuation of the key CD28/B7-2 co-stimulatory pathway without full inhibition, Reltecimod TFA is utilized in researching necrotizing soft-tissue infections (NSTIs) [1].

Reltecimod TFA
Other Forms of Reltecimod TFA:

Reltecimod TFA

😃Good
Catalog No. T78107Alias AB-103 TFA
Reltecimod (AB-103) TFA is an antagonist of the T-cell-specific surface glycoprotein CD28 (TP44), demonstrating efficacy against various bacterial infections, including exotoxins, endotoxins, and ionizing radiation. By modulating the inflammatory response through attenuation of the key CD28/B7-2 co-stimulatory pathway without full inhibition, Reltecimod TFA is utilized in researching necrotizing soft-tissue infections (NSTIs) [1].
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2 mg$305 days
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Product Introduction

Bioactivity
Description
Reltecimod (AB-103) TFA is an antagonist of the T-cell-specific surface glycoprotein CD28 (TP44), demonstrating efficacy against various bacterial infections, including exotoxins, endotoxins, and ionizing radiation. By modulating the inflammatory response through attenuation of the key CD28/B7-2 co-stimulatory pathway without full inhibition, Reltecimod TFA is utilized in researching necrotizing soft-tissue infections (NSTIs) [1].
In vivo
Reltecimod, administered intravenously at dosages ranging from 1.25 to 5 mg/kg, has been shown to enhance survival rates in mice infected with various bacteria [1].
AliasAB-103 TFA
Chemical Properties
Molecular Weight1037.19 (free base)
FormulaC46H72N10O15S.xC2HF3O2
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Reltecimod TFA
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