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RET-IN-1

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Catalog No. T16735Cas No. 2222755-14-6

RET-IN-1 is a RET kinase inhibitor with IC50 values of 1 nM for RET (WT), 7 nM for RET (V804M), and 101 nM for RET (G810R).

RET-IN-1

RET-IN-1

😃Good
Catalog No. T16735Cas No. 2222755-14-6
RET-IN-1 is a RET kinase inhibitor with IC50 values of 1 nM for RET (WT), 7 nM for RET (V804M), and 101 nM for RET (G810R).
Pack SizePriceAvailabilityQuantity
25 mg$2,57010-14 weeks
50 mg$3,38010-14 weeks
100 mg$4,60010-14 weeks
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Product Introduction

Bioactivity
Description
RET-IN-1 is a RET kinase inhibitor with IC50 values of 1 nM for RET (WT), 7 nM for RET (V804M), and 101 nM for RET (G810R).
Targets&IC50
RETWT:1 nM, RETV804M:7 nM, RET (G810R):101 nM
Chemical Properties
Molecular Weight553.61
FormulaC29H31N9O3
Cas No.2222755-14-6
Relative Density.1.49 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

RETWTRETV804MRET-IN-1RETIN1RETG810RRET IN 1
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