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Ricinelaidic acid is a 12-hydroxy fatty acid and an antagonist of leukotriene B4 (LTB4) receptors (Ki = 2 μM in porcine neutrophil membranes). It inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50s = 10 and 7 μM, respectively). Ricinelaidic acid (1 mg/kg, i.v.) inhibits bronchoconstriction induced by LTB4 in rats by 46%.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | $540 | 35 days | |
250 mg | $1,190 | 35 days |
Description | Ricinelaidic acid is a 12-hydroxy fatty acid and an antagonist of leukotriene B4 (LTB4) receptors (Ki = 2 μM in porcine neutrophil membranes). It inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50s = 10 and 7 μM, respectively). Ricinelaidic acid (1 mg/kg, i.v.) inhibits bronchoconstriction induced by LTB4 in rats by 46%. |
Molecular Weight | 298.46 |
Formula | C18H34O3 |
Cas No. | 540-12-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
Solubility Information | Ethanol: Miscible DMF: 3 mg/mL (10.05 mM), Sonication is recommended. DMSO: 2 mg/mL (6.7 mM), Sonication is recommended. PBS (pH 7.2): 2 mg/mL (6.7 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO/PBS (pH 7.2)/DMF
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