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Rugonersen sodium is a locked nucleic acid (LNA)-modified antisense oligonucleotide (ASO) designed to reduce the silencing of ubiquitin protein ligase E3A (UBE3A). Angelman syndrome (AS) refers to a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A, and Rugonersen has been studied for its potential use in the treatment of AS.
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10 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Rugonersen sodium is a locked nucleic acid (LNA)-modified antisense oligonucleotide (ASO) designed to reduce the silencing of ubiquitin protein ligase E3A (UBE3A). Angelman syndrome (AS) refers to a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A, and Rugonersen has been studied for its potential use in the treatment of AS. |
Alias | RO7248824 sodium, RG6091 sodium |
Molecular Weight | 6948.00 |
Formula | C204H235N63Na19O109P19S19 |
Cas No. | 2591588-58-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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