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S-(N-PhenethylthiocarbaMoyl)-L-cysteine
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Catalog No. T60559Cas No. 53330-02-2
S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys) is an anticarcinogenic agent that exhibits antileukemic activity by inhibiting DNA synthesis in HL60 cells [1] and acts as an inhibitor of P450 [2].
S-(N-PhenethylthiocarbaMoyl)-L-cysteine
😃Good
Catalog No. T60559Cas No. 53330-02-2
S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys) is an anticarcinogenic agent that exhibits antileukemic activity by inhibiting DNA synthesis in HL60 cells [1] and acts as an inhibitor of P450 [2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $2,140 | 6-8 weeks | |
| 50 mg | $2,785 | 6-8 weeks | |
| 100 mg | $3,520 | 6-8 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys) is an anticarcinogenic agent that exhibits antileukemic activity by inhibiting DNA synthesis in HL60 cells [1] and acts as an inhibitor of P450 [2]. |
| In vitro | S-(N-PhenethylthiocarbaMoyl)-L-cysteine exhibits significant anti-proliferative effects on HL60 cells by inhibiting cell growth and DNA synthesis, and inducing DNA fragmentation. It has a GC50 value of 336 nM and an IC50 value of 6.47 μM for DNA synthesis. Treatment with concentrations of 0.1 to 10 μM for 48 hours restricts cell growth, with consistent effects up to 100 hours at 4 μM [1]. |
| Molecular Weight | 284.4 |
| Formula | C12H16N2O2S2 |
| Cas No. | 53330-02-2 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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