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S16–1029

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Catalog No. T87351Cas No. 2653349-51-8

S16–1029 is a selective, orally active butyrylcholinesterase (BChE) inhibitor with IC50 values of 11.35 nM for eqBChE and 48.1 nM for hBChE. It can cross the blood-brain barrier (BBB) and reach the central nervous system (CNS), making it suitable for Alzheimer's disease (AD) research [1].

S16–1029

S16–1029

😃Good
Catalog No. T87351Cas No. 2653349-51-8
S16–1029 is a selective, orally active butyrylcholinesterase (BChE) inhibitor with IC50 values of 11.35 nM for eqBChE and 48.1 nM for hBChE. It can cross the blood-brain barrier (BBB) and reach the central nervous system (CNS), making it suitable for Alzheimer's disease (AD) research [1].
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
S16–1029 is a selective, orally active butyrylcholinesterase (BChE) inhibitor with IC50 values of 11.35 nM for eqBChE and 48.1 nM for hBChE. It can cross the blood-brain barrier (BBB) and reach the central nervous system (CNS), making it suitable for Alzheimer's disease (AD) research [1].
Targets&IC50
eqBCHE:11.35 nM, hBCHE:48.1 nM
Chemical Properties
Molecular Weight447.49
FormulaC23H25N7O3
Cas No.2653349-51-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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