Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact Us
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TOPBioactivityChemical infoStorage&SolubilityCalculator

SBN-284

😃Good
Catalog No. T88928

SBN-284 (compound 3x) acts as a dual inhibitor of cholinesterases (Cholinesterases) and NLRP3 inflammasomes, demonstrating blood-brain barrier permeability. It exhibits IC50 values of 0.37, 0.31, and 0.29 μM against EeAChE, hAChE, and eqBChE respectively, and an EC50 value of 1 μM against NLRP3. SBN-284 is utilized in Alzheimers disease research.

SBN-284

SBN-284

😃Good
Catalog No. T88928
SBN-284 (compound 3x) acts as a dual inhibitor of cholinesterases (Cholinesterases) and NLRP3 inflammasomes, demonstrating blood-brain barrier permeability. It exhibits IC50 values of 0.37, 0.31, and 0.29 μM against EeAChE, hAChE, and eqBChE respectively, and an EC50 value of 1 μM against NLRP3. SBN-284 is utilized in Alzheimers disease research.
Pack SizePriceAvailabilityQuantity
10 mgInquiryBackorder
50 mgInquiryBackorder
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
SBN-284 (compound 3x) acts as a dual inhibitor of cholinesterases (Cholinesterases) and NLRP3 inflammasomes, demonstrating blood-brain barrier permeability. It exhibits IC50 values of 0.37, 0.31, and 0.29 μM against EeAChE, hAChE, and eqBChE respectively, and an EC50 value of 1 μM against NLRP3. SBN-284 is utilized in Alzheimers disease research.
Targets&IC50
NLRP3 inflammasome:1 μM (EC50), Ee AChE:0.37 μM, hAChE:0.31 μM, eqBCHE:0.29 μM
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy SBN-284 | purchase SBN-284 | SBN-284 cost | order SBN-284
TargetMol | Logo

Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.