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SHR1653

Catalog No. T12904Cas No. 2231770-73-1

SHR1653 is a highly potent, selective, and brain-penetrating antagonist of the oxytocin receptor (OTR) with an IC50 of 15 nM for hOTR.

SHR1653

SHR1653

Catalog No. T12904Cas No. 2231770-73-1
SHR1653 is a highly potent, selective, and brain-penetrating antagonist of the oxytocin receptor (OTR) with an IC50 of 15 nM for hOTR.
Pack SizePriceAvailabilityQuantity
25 mg$8936-8 weeks
50 mg$1,1606-8 weeks
100 mg$1,9006-8 weeks
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Product Introduction

Bioactivity
Description
SHR1653 is a highly potent, selective, and brain-penetrating antagonist of the oxytocin receptor (OTR) with an IC50 of 15 nM for hOTR.
Targets&IC50
OTR (human):15 nM
Chemical Properties
Molecular Weight429.88
FormulaC21H21ClFN5O2
Cas No.2231770-73-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

SHR-1653SHR1653SHR 1653
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