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SIAIS117

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Catalog No. T74489Cas No. 2353494-84-3

SIAIS117, a potent Brigatinib-PROTAC degrader, effectively degrades the ALK G1202R point mutation through its design based on Brigatinib and VHL-1 conjunction. It inhibits the proliferation of SR and H2228 cancer cell lines, demonstrating potential anti-proliferative effects against small cell lung cancer [1].

SIAIS117

SIAIS117

😃Good
Catalog No. T74489Cas No. 2353494-84-3
SIAIS117, a potent Brigatinib-PROTAC degrader, effectively degrades the ALK G1202R point mutation through its design based on Brigatinib and VHL-1 conjunction. It inhibits the proliferation of SR and H2228 cancer cell lines, demonstrating potential anti-proliferative effects against small cell lung cancer [1].
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Product Introduction

Bioactivity
Description
SIAIS117, a potent Brigatinib-PROTAC degrader, effectively degrades the ALK G1202R point mutation through its design based on Brigatinib and VHL-1 conjunction. It inhibits the proliferation of SR and H2228 cancer cell lines, demonstrating potential anti-proliferative effects against small cell lung cancer [1].
Chemical Properties
Molecular Weight1111.77
FormulaC57H76ClN10O7PS
Cas No.2353494-84-3
Storage & Solubility Information
StorageShipping with blue ice.

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