Name: SMP-797 HCl
Brand: TargetMol
SKU: T28820
Rating: 4.5 (1 reviews)

SMP-797 HCl

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Catalog No. T28820Alias SMP-797, SMP797, SMP 797Cas No. 259224-95-8

SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia.

Pack Size	Price	Availability
25 mg	$2,420	10-14 weeks
50 mg	$3,180	10-14 weeks
100 mg	$4,300	10-14 weeks

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QDoes the compound differ in any way when it is in the form of hydrochloride or sulfate ions? What is the difference between the salt form and the free form?

AThe molecules in salt and non-salt forms exhibit the same activity, and they have consistent effects in biological experiments. Their activity and usage are identical. The only difference lies in their salt forms, which may result in variations in physical properties such as solubility. It is recommended to choose based on solubility and experimental requirements.

QWhat’s pIC50?

ApIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).

QWhat’s IC50?

AHalf-maximal inhibitory concentration (IC50) refers to the concentration of the inhibitor which is required to inhibit a given biological or biochemical function by half.

QWhat’s ED50?

AEffective dose 50 (ED50）refers to the dose of a drug that produces a specific effect in 50% of the population that has been administered that dose.

QWhat’s EC50?

AHalf maximal effective concentratioin(EC50) refers to the concentration of a compound that achieves 50% of the maximum effect(inhibitory/stimulatory effect),after a specified exposure duration.

Product Introduction

Bioactivity

Description	SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia.
Alias	SMP-797, SMP797, SMP 797

Chemical Properties

Molecular Weight	622.20
Formula	C₃₄H₄₄ClN₅O₄
Cas No.	259224-95-8
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.