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Sulfo-ara-F-NMN

Catalog No. T13907Cas No. 1374663-29-2
Alias CZ-48

Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NMN to Z-48 or NMN, which has a higher cyclase activity, causes conformational changes in SARM1, resulting in cADPR production, NAD depletion, and non-apoptotic cell death.

Sulfo-ara-F-NMN
Other Forms of Sulfo-ara-F-NMN:
Camptothecin-20(S)-O-propionateT27113194414-69-2
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Sulfo-ara-F-NMN

Catalog No. T13907Alias CZ-48Cas No. 1374663-29-2
Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NMN to Z-48 or NMN, which has a higher cyclase activity, causes conformational changes in SARM1, resulting in cADPR production, NAD depletion, and non-apoptotic cell death.
Pack SizePriceAvailabilityQuantity
25 mg$2,4806-8 weeks
50 mg$3,9906-8 weeks
100 mg$6,2906-8 weeks
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Product Introduction

Bioactivity
Description
Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NMN to Z-48 or NMN, which has a higher cyclase activity, causes conformational changes in SARM1, resulting in cADPR production, NAD depletion, and non-apoptotic cell death.
AliasCZ-48
Chemical Properties
Molecular Weight352.28
FormulaC11H14FN2O6PS
Cas No.1374663-29-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Keywords

SulfoaraFNMNSulfo ara F NMNCZ 48CZ48Sulfo-ara-F-NMN
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