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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | SZUH280 is a potent, selective PROTAC (proteolysis targeting chimera) HDAC8 (histone deacetylase 8) degrader, demonstrating a DC50 of 0.58 μM in A549 cells. It induces apoptosis in cancer cells and impedes DNA damage repair, thereby enhancing cellular radiosensitization [1]. |
Molecular Weight | 706.7 |
Formula | C36H34N8O8 |
Cas No. | 2770263-77-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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