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T-10418 is an agonist of the G2 accumulation protein (G2A), also known as G protein-coupled receptor GPR132, with an EC50 of 0.82 μM. It sensitizes primary sensory neurons in mice and demonstrates favorable pharmacokinetic properties in mouse models without significant toxicity at concentrations up to 100 μM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | T-10418 is an agonist of the G2 accumulation protein (G2A), also known as G protein-coupled receptor GPR132, with an EC50 of 0.82 μM. It sensitizes primary sensory neurons in mice and demonstrates favorable pharmacokinetic properties in mouse models without significant toxicity at concentrations up to 100 μM. |
Molecular Weight | 376.41 |
Formula | C22H20N2O4 |
Cas No. | 1608784-68-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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