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TBK1 control PROTAC® 4

Name: TBK1 control PROTAC® 4
Brand: TargetMol
SKU: T36247
Rating: 4.5 (1 reviews)

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Catalog No. T36247Cas No. 2052306-31-5

Negative control for TBK1 PROTAC 3i. Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

TBK1 control PROTAC® 4

😃Good

Catalog No. T36247Cas No. 2052306-31-5

Pack Size	Price	Availability	Quantity
5 mg	$1,070	35 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	1093.19
Formula	C₅₃H₇₄BrN₉O₉S
Cas No.	2052306-31-5
Relative Density.	1.312 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 109.32 mg/mL (100 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.9148 mL	4.5738 mL	9.1475 mL	45.7377 mL
5 mM	0.1830 mL	0.9148 mL	1.8295 mL	9.1475 mL
10 mM	0.0915 mL	0.4574 mL	0.9148 mL	4.5738 mL
20 mM	0.0457 mL	0.2287 mL	0.4574 mL	2.2869 mL
50 mM	0.0183 mL	0.0915 mL	0.1830 mL	0.9148 mL
100 mM	0.0091 mL	0.0457 mL	0.0915 mL	0.4574 mL

Calculator

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Dilution Calculator
Reconstitution Calculator
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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TBK1 control PROTAC® 4TBK-1 control PROTAC® 4