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TBK1 control PROTAC® 4

TBK1 control PROTAC® 4
Contact us for more batch information

TBK1 control PROTAC® 4

Catalog No. T36247Cas No. 2052306-31-5
Negative control for TBK1 PROTAC 3i. Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$1,07035 days
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Product Introduction

Bioactivity
Description
Negative control for TBK1 PROTAC 3i. Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
Chemical Properties
Molecular Weight1093.19
FormulaC53H74BrN9O9S
Cas No.2052306-31-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 109.32 mg/mL(100 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.9148 mL4.5738 mL9.1475 mL45.7377 mL
5 mM0.1830 mL0.9148 mL1.8295 mL9.1475 mL
10 mM0.0915 mL0.4574 mL0.9148 mL4.5738 mL
20 mM0.0457 mL0.2287 mL0.4574 mL2.2869 mL
50 mM0.0183 mL0.0915 mL0.1830 mL0.9148 mL
100 mM0.0091 mL0.0457 mL0.0915 mL0.4574 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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