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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | TCO-PEG3-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system [in cells]. |
In vitro | PROTACs consist of two distinct ligands linked together: one targets an E3 ubiquitin ligase, and the other binds to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Molecular Weight | 470.519 |
Formula | C22H34N2O9 |
Cas No. | 2141981-88-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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