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Tetrahydro-11-deoxy Cortisol

🥰Excellent
Catalog No. T36472Cas No. 68-60-0

Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cytochrome P450 (CYP) isoform CYP11B1. Urinary levels of THS are also elevated in patients with adrenocortical carcinoma (ACC) and adrenocortical adenoma (ACA) but are higher in patients with ACC compared to ACA.

Tetrahydro-11-deoxy Cortisol

Tetrahydro-11-deoxy Cortisol

🥰Excellent
Catalog No. T36472Cas No. 68-60-0
Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cytochrome P450 (CYP) isoform CYP11B1. Urinary levels of THS are also elevated in patients with adrenocortical carcinoma (ACC) and adrenocortical adenoma (ACA) but are higher in patients with ACC compared to ACA.
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Product Introduction

Bioactivity
Description
Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cytochrome P450 (CYP) isoform CYP11B1. Urinary levels of THS are also elevated in patients with adrenocortical carcinoma (ACC) and adrenocortical adenoma (ACA) but are higher in patients with ACC compared to ACA.
Chemical Properties
Molecular Weight350.499
FormulaC21H34O4
Cas No.68-60-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL
Ethanol:PBS(pH 7.2) (1:1): 0.2 mg/mL
Ethanol: 30 mg/mL
DMF: 30 mg/mL

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Keywords

Tetrahydro11deoxy CortisolTetrahydro-11-deoxy CortisolTetrahydro 11 deoxy Cortisol
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