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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | Inquiry | 7-10 days | |
50 mg | Inquiry | 7-10 days | |
100 mg | Inquiry | 7-10 days |
Description | Thalidomide-O-amido-PEG-C2-NH2 is a synthesized conjugate formulation designed as an E3 ligase ligand-linker conjugate. It incorporates a cereblon ligand based on Thalidomide and a linker component commonly utilized in PROTAC technology. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Alias | Thalidomide-O-amido-PEG-C2-NH2 |
Molecular Weight | 418.4 |
Formula | C19H22N4O7 |
Cas No. | 2022182-59-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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