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Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Thalidomide-O-amido-PEG4-C2-NH2 is a synthesized conjugate compound that combines a Thalidomide-based cereblon ligand with a linker commonly used in PROTAC technology. It acts as an E3 ligase ligand-linker conjugate, enabling targeted protein degradation. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Alias | Thalidomide-O-amido-PEG4-C2-NH2 |
Molecular Weight | 550.565 |
Formula | C25H34N4O10 |
Cas No. | 1957236-22-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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