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Thalidomide-alkyne-C4-NHBoc

Name: Thalidomide-alkyne-C4-NHBoc
Brand: TargetMol
SKU: T89993
Rating: 4.5 (1 reviews)

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Catalog No. T89993Cas No. 2093387-85-8

Thalidomide-alkyne-C4-NHBoc serves as an E3 Ligase Ligand-Linker Conjugate. It is utilized in the synthesis of PROTAC JAK1 degrader 1.

Thalidomide-alkyne-C4-NHBoc

😃Good

Catalog No. T89993Cas No. 2093387-85-8

Thalidomide-alkyne-C4-NHBoc serves as an E3 Ligase Ligand-Linker Conjugate. It is utilized in the synthesis of PROTAC JAK1 degrader 1.

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Product Introduction

Bioactivity

Description

Thalidomide-alkyne-C4-NHBoc serves as an E3 Ligase Ligand-Linker Conjugate. It is utilized in the synthesis of PROTAC JAK1 degrader 1.

Chemical Properties

Molecular Weight	453.49
Formula	C₂₄H₂₇N₃O₆
Cas No.	2093387-85-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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