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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $39 | 5 days |
Description | Thiol-PEG8-alcohol is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, comprising two distinct ligands joined by a linker—one binding to an E3 ubiquitin ligase and the other to a target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | HS-PEG8-OH |
Molecular Weight | 386.5 |
Formula | C16H34O8S |
Cas No. | 791620-96-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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