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Thiomarinol A

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Catalog No. T73673Cas No. 146697-04-3

Thiomarinol A (4-Hydroxythiomarinol C), a potent antibiotic, is a hybrid compound comprising dithiolopyrrolone and marinolic acid, exhibiting antimicrobial activity. It effectively inhibits MRSA IleRS in a dose-dependent manner, with an apparent K_i value of 19 nM [1].

Thiomarinol A

Thiomarinol A

😃Good
Catalog No. T73673Cas No. 146697-04-3
Thiomarinol A (4-Hydroxythiomarinol C), a potent antibiotic, is a hybrid compound comprising dithiolopyrrolone and marinolic acid, exhibiting antimicrobial activity. It effectively inhibits MRSA IleRS in a dose-dependent manner, with an apparent K_i value of 19 nM [1].
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Product Introduction

Bioactivity
Description
Thiomarinol A (4-Hydroxythiomarinol C), a potent antibiotic, is a hybrid compound comprising dithiolopyrrolone and marinolic acid, exhibiting antimicrobial activity. It effectively inhibits MRSA IleRS in a dose-dependent manner, with an apparent K_i value of 19 nM [1].
Chemical Properties
Molecular Weight640.81
FormulaC30H44N2O9S2
Cas No.146697-04-3
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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