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TLR7 agonist20 hydrochloride is an imidazoquinoline analog that functions as a potent and specific agonist for TLR7, with an EC50 value of 0.23 μM against hTLR7. It demonstrates strong adjuvant activity in enhancing spike antibody levels and induces a robust T helper cell 1 (Th1) response. Additionally, it increases levels of IgG2b and IgG2c, aside from IgG1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | TLR7 agonist20 hydrochloride is an imidazoquinoline analog that functions as a potent and specific agonist for TLR7, with an EC50 value of 0.23 μM against hTLR7. It demonstrates strong adjuvant activity in enhancing spike antibody levels and induces a robust T helper cell 1 (Th1) response. Additionally, it increases levels of IgG2b and IgG2c, aside from IgG1. |
Targets&IC50 | TLR8:17.21 μM (EC50), TLR7:0.23 μM (EC50) |
Molecular Weight | 396.91 |
Formula | C22H25ClN4O |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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