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Trevogrumab

Catalog No. T80951Cas No. 1429201-24-0
Alias REGN-1033

Trevogrumab (REGN-1033), a monoclonal antibody targeting GDF8 (growth differentiation factor 8, also known as muscle growth inhibitor), is currently under investigation for the treatment of sarcopenia, characterized by wasting atrophy, chronic diseases, and alterations in dietary and nutritional intake [1].

Trevogrumab

Trevogrumab

Catalog No. T80951Alias REGN-1033Cas No. 1429201-24-0
Trevogrumab (REGN-1033), a monoclonal antibody targeting GDF8 (growth differentiation factor 8, also known as muscle growth inhibitor), is currently under investigation for the treatment of sarcopenia, characterized by wasting atrophy, chronic diseases, and alterations in dietary and nutritional intake [1].
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Bioactivity
Description
Trevogrumab (REGN-1033), a monoclonal antibody targeting GDF8 (growth differentiation factor 8, also known as muscle growth inhibitor), is currently under investigation for the treatment of sarcopenia, characterized by wasting atrophy, chronic diseases, and alterations in dietary and nutritional intake [1].
AliasREGN-1033
Chemical Properties
Cas No.1429201-24-0
Storage & Solubility Information
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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