Trichloroacetic acid, commonly used for facial chemical resurfacing, is a metabolite of trichloroethylene, believed to contribute to its hepatocarcinogenic effects in mice.

Trichloroacetic acid (TCA), a prevalent byproduct of drinking water disinfection, induces a range of liver effects in mice, such as hepatomegaly and liver tumors. Additionally, it serves as an oxidative metabolite of trichloroethylene (TCE), a commonly used degreasing solvent subject to extensive environmental exposure, similarly resulting in hepatomegaly and liver tumors in mice[3].