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Triton X-100

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Catalog No. T64297Cas No. 9002-93-1

Triton X-100 is a non-denaturing detergent that solubilizes lipid membranes. Triton X-100 is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Triton X-100 is listed as an excipient in certain vaccines including split virus influenza vaccines. Triton X-100 is a nonionic surfactant [1] [2].

Triton X-100

Triton X-100

🥰Excellent
Catalog No. T64297Cas No. 9002-93-1
Triton X-100 is a non-denaturing detergent that solubilizes lipid membranes. Triton X-100 is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Triton X-100 is listed as an excipient in certain vaccines including split virus influenza vaccines. Triton X-100 is a nonionic surfactant [1] [2].
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Product Introduction

Bioactivity
Description
Triton X-100 is a non-denaturing detergent that solubilizes lipid membranes. Triton X-100 is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Triton X-100 is listed as an excipient in certain vaccines including split virus influenza vaccines. Triton X-100 is a nonionic surfactant [1] [2].
In vitro
Triton X-100 (ranging from 0.5% to 0.05%; 1 h; Vero E6 cells) obtained with WNV showed that infectivity was reduced by 6 Logs. This effect was not time-dependent using 0.1% Triton X-100. We applied the method to EBOV and one-hour exposure to 0.1% Triton X-100 strongly affected EBOV infectivity (4 Logs of infectivity reduction).[3]
Chemical Properties
Molecular Weight208.26
FormulaC14H12N2
Cas No.9002-93-1
SmilesN.CC(C)(C)CC(C)(C)c1ccc(OCCO)cc1
Storage & Solubility Information
Storagekeep away from moisture | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (216.08 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.8017 mL24.0085 mL48.0169 mL240.0845 mL
5 mM0.9603 mL4.8017 mL9.6034 mL48.0169 mL
10 mM0.4802 mL2.4008 mL4.8017 mL24.0085 mL
20 mM0.2401 mL1.2004 mL2.4008 mL12.0042 mL
50 mM0.0960 mL0.4802 mL0.9603 mL4.8017 mL
100 mM0.0480 mL0.2401 mL0.4802 mL2.4008 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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