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TRK-IN-21

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Catalog No. T62286Cas No. 2429985-55-5

TRK-IN-21 (5n) is an orally active TRK inhibitor that acts on TRKAWT (IC50: 0.3 nM), TRKAG667C (IC50: 2.3 nM), TRKAF589L (IC50: 0.4 nM), and TRKAG595 (IC50: 0.5 nM). TRK-IN-21 can be used to study cancer.

TRK-IN-21

TRK-IN-21

😃Good
Catalog No. T62286Cas No. 2429985-55-5
TRK-IN-21 (5n) is an orally active TRK inhibitor that acts on TRKAWT (IC50: 0.3 nM), TRKAG667C (IC50: 2.3 nM), TRKAF589L (IC50: 0.4 nM), and TRKAG595 (IC50: 0.5 nM). TRK-IN-21 can be used to study cancer.
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
TRK-IN-21 (5n) is an orally active TRK inhibitor that acts on TRKAWT (IC50: 0.3 nM), TRKAG667C (IC50: 2.3 nM), TRKAF589L (IC50: 0.4 nM), and TRKAG595 (IC50: 0.5 nM). TRK-IN-21 can be used to study cancer.
Chemical Properties
Molecular Weight424.45
FormulaC22H22F2N6O
Cas No.2429985-55-5
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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