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Trx-red

Name: Trx-red
Brand: TargetMol
SKU: T39915
Rating: 4.5 (1 reviews)

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Catalog No. T39915Cas No. 2368978-96-3

Alias Trx-red, NBL-SS perchlorate

Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derived from the Nile blue fluorophore, specifically designed for imaging thioredoxin (Trx) in live cells and in vivo, with excitation and emission wavelengths of 615 nm and 661 nm, respectively.

Trx-red

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Catalog No. T39915Alias Trx-red, NBL-SS perchlorateCas No. 2368978-96-3

Pack Size	Price	Availability	Quantity
25 mg	$822	Backorder

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Product Introduction

Bioactivity

Description	Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derived from the Nile blue fluorophore, specifically designed for imaging thioredoxin (Trx) in live cells and in vivo, with excitation and emission wavelengths of 615 nm and 661 nm, respectively.
In vitro	Trx-red (NBL-SS) exhibits several advantageous characteristics, including red emission, rapid response, and heightened fluorescence signal. Thioredoxin (Trx) plays a critical role in cellular processes such as growth, differentiation, and apoptosis, functioning as a widespread redox-regulating protein[1]. Notably, upon incubating HeLa cells with Trx-red (NBL-SS; 5 μM; 0-30 min), a significant time-dependent escalation in fluorescence is evident[1].
In vivo	Trx-red (NBL-SS; 10 μM; 30 min) effectively images thioredoxin in 6-day-old zebrafish larvae [1].
Alias	Trx-red, NBL-SS perchlorate

Chemical Properties

Molecular Weight	714.15
Formula	C₂₉H₃₂ClN₃O₁₂S₂
Cas No.	2368978-96-3
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NBL-SS PerchlorateTrxredTrx red