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UCM-13369

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Catalog No. T87591Cas No. 2921944-77-4

UCM-13369 (Compound 4b) serves as an NPM1 inhibitor, effectively downregulating the pathway linked to mutant NPM1 C+ by specifically targeting the C-terminal DNA-binding domain of NPM1 C+. It induces apoptosis in AML cell lines and primary cells, making it a valuable tool for AML research [1].

UCM-13369

UCM-13369

😃Good
Catalog No. T87591Cas No. 2921944-77-4
UCM-13369 (Compound 4b) serves as an NPM1 inhibitor, effectively downregulating the pathway linked to mutant NPM1 C+ by specifically targeting the C-terminal DNA-binding domain of NPM1 C+. It induces apoptosis in AML cell lines and primary cells, making it a valuable tool for AML research [1].
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
UCM-13369 (Compound 4b) serves as an NPM1 inhibitor, effectively downregulating the pathway linked to mutant NPM1 C+ by specifically targeting the C-terminal DNA-binding domain of NPM1 C+. It induces apoptosis in AML cell lines and primary cells, making it a valuable tool for AML research [1].
Chemical Properties
Molecular Weight389.53
FormulaC25H31N3O
Cas No.2921944-77-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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