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VK-1727
VK-1727
VK-1727, a selective small molecule inhibitor of EBNA1, diminishes the DNA binding activity of EBNA1 and curtails the proliferation and metabolic activity of EBV+ cells while not affecting EBV- cells. This compound is utilized in research pertaining to multiple sclerosis [1].
Catalog No. T78598
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VK-1727
Catalog No. T78598
VK-1727, a selective small molecule inhibitor of EBNA1, diminishes the DNA binding activity of EBNA1 and curtails the proliferation and metabolic activity of EBV+ cells while not affecting EBV- cells. This compound is utilized in research pertaining to multiple sclerosis [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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| Description | VK-1727, a selective small molecule inhibitor of EBNA1, diminishes the DNA binding activity of EBNA1 and curtails the proliferation and metabolic activity of EBV+ cells while not affecting EBV- cells. This compound is utilized in research pertaining to multiple sclerosis [1]. |
| In vitro | VK-1727 (25 μM, 72 hours) significantly reduced the total number of G2 cells in EBV+ cells [1]. |
| Molecular Weight | 451.51 |
| Formula | C29H25NO4 |
| Cas No. |
| Storage | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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