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VU0506013

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Catalog No. TP2947Cas No. 1207036-87-0
Alias VU0506013-1, SR-01000917304-1, SR-01000917304, F2947-0623, AKOS024476467

VU0506013 is a high-affinity positive allosteric modulator (PAM) of the neuropeptide Y4 receptor. This compound demonstrates nanomolar-level affinity and notable selectivity in engineered cell lines and the descending colon mucosa of mice that naturally express Y4R. VU0506013 presents a promising foundation for developing in vivo tools aimed at advancing anti-obesity compound research targeting Y4R.

VU0506013

VU0506013

😃Good
Catalog No. TP2947Alias VU0506013-1, SR-01000917304-1, SR-01000917304, F2947-0623, AKOS024476467Cas No. 1207036-87-0
VU0506013 is a high-affinity positive allosteric modulator (PAM) of the neuropeptide Y4 receptor. This compound demonstrates nanomolar-level affinity and notable selectivity in engineered cell lines and the descending colon mucosa of mice that naturally express Y4R. VU0506013 presents a promising foundation for developing in vivo tools aimed at advancing anti-obesity compound research targeting Y4R.
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Product Introduction

Bioactivity
Description
VU0506013 is a high-affinity positive allosteric modulator (PAM) of the neuropeptide Y4 receptor. This compound demonstrates nanomolar-level affinity and notable selectivity in engineered cell lines and the descending colon mucosa of mice that naturally express Y4R. VU0506013 presents a promising foundation for developing in vivo tools aimed at advancing anti-obesity compound research targeting Y4R.
AliasVU0506013-1, SR-01000917304-1, SR-01000917304, F2947-0623, AKOS024476467
Chemical Properties
Molecular Weight369.41
FormulaC20H23N3O4
Cas No.1207036-87-0
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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