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Description | Warfarin (Coumafene) is a vitamin K antagonist, and it works by blocking the action of vitamin K, which is necessary for the synthesis of clotting factors in the liver. Warfarin blocks the action of vitamin K by inhibiting the enzyme gamma-glutamyl carboxylase, which is responsible for the carboxylation of glutamate residues in the clotting factors. This prevents the production of functional clotting factors, leading to an anticoagulant effect. |
Alias | Athrombine-K, Prothromadin, Coumafene, Coumadin, WARF-42 |
Molecular Weight | 308.3279 |
Formula | C19H16O4 |
Cas No. | 81-81-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 40 mg/mL (129.73 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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