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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $59 | 5 days |
Description | YZ129, a glioblastoma inhibitor, targets the HSP90-calcineurin-NFAT pathway by directly binding to heat shock protein 90 (HSP90) and exhibits an IC 50 of 820 nM on NFAT nuclear translocation. It induces cell-cycle arrest at the G2/M phase in GBM cells, leading to apoptosis and inhibiting tumor cell proliferation and migration [1]. |
Molecular Weight | 300.31 |
Formula | C19H12N2O2 |
Cas No. | 1643120-60-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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