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Z19153

Catalog No. T88602Cas No. 2600702-14-3

Z19153 is a PDE4 inhibitor with IC50 values of 110 nM for PDE4B1 and 1160 nM for PDE4D7. It exhibits significant hepatoprotective effects in cases of hepatic sepsis.

Z19153

Z19153

Catalog No. T88602Cas No. 2600702-14-3
Z19153 is a PDE4 inhibitor with IC50 values of 110 nM for PDE4B1 and 1160 nM for PDE4D7. It exhibits significant hepatoprotective effects in cases of hepatic sepsis.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
Z19153 is a PDE4 inhibitor with IC50 values of 110 nM for PDE4B1 and 1160 nM for PDE4D7. It exhibits significant hepatoprotective effects in cases of hepatic sepsis.
Targets&IC50
PDE4D7:1160 nM, PDE4B1:110 nM
Chemical Properties
Molecular Weight247.33
FormulaC15H21NO2
Cas No.2600702-14-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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