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Bromo-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules and facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Bromo-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules and facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands joined by a linker: one binds to an E3 ubiquitin ligase, while the other targets a specific protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 329.18 |
Formula | C11H21BrO6 |
Cas No. | 1393330-38-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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